Since turn of 2001, I've found that sitting for prolonged periods of time causes me to get pain in my abdomen. There are medical reasons for this, but I won't go into details here. Needless to say, my chosen profession means I spend 90% of my working day in front of a computer screen and up until now that's meant sitting down.
Recently, I saw an article on Yewhealth which led me to consider swapping my home office space to a Standing Desk.